Postconditioning: a new or old option after ischemic stroke?
نویسندگان
چکیده
منابع مشابه
Two year-old boy with ischemic stroke
Arterial ischemic stroke (AIS) in adults is considered a serious health threat and requires urgent medical treatment. Prompt diagnosis allows the therapeutic option of thrombolysis within the time window of 3 to 6 hours after first symptoms. Alternatively, early anti-platelet therapy is effective in improving the outcome after stroke. The incidence of pediatric AIS range from 2 to 5 per 100 000...
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Cerebral ischemic preconditioning protects against stroke, but is clinically feasible only when the occurrence of stroke is predictable. Reperfusion plays a critical role in cerebral injury after stroke; we tested the hypothesis that interrupting reperfusion lessens ischemic injury. We found for the first time that such postconditioning with a series of mechanical interruptions of reperfusion s...
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BACKGROUND Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during the first 3 months after a transient ischemic attack (TIA) or minor stroke. The TIAregistry.org project was designed to describe the contemporary profile, etiologic factors, and outcomes in patients with a TIA or minor ischemic stroke who receive care ...
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Background & Aims: Ischemic postconditioning, conducted by a series of brief occlusion and release of the bilateral common carotid arteries, has neuroprotective properties in permanent or transient models of middle cerebral artery (MCA) occlusion but its delayed neuroprotective effects in the embolic model of stroke, especially in female rat, have not yet been reported and were investigated ...
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meta-analysis of three randomized clinical trials including ISAT did not show a significant difference in outcomes between patients treated with these two options. Despite limitations of ISAT, this is a wellexecuted trial that highlights the necessity of long-term follow-up in aneurysmal SAH patients. The increased rate of rebleeding in untreated and de novo aneurysms underscores that clipping ...
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ژورنال
عنوان ژورنال: Expert Review of Cardiovascular Therapy
سال: 2010
ISSN: 1477-9072,1744-8344
DOI: 10.1586/erc.09.180